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Comparison of Estimates between Cohort and Case–Control Studies in Meta-Analyses of Therapeutic Interventions: A Meta-Epidemiological Study

Fig 3

Sensitivity analysis of differences in effect estimates between case–control and cohort studies with available data on adjusted estimates.

Difference in treatment effect estimates is expressed as ratio of estimates (RE). A RE < 1 indicates that case–control studies yielded larger estimates of the intervention effect or adverse events than cohort studies.

Fig 3

doi: https://doi.org/10.1371/journal.pone.0154877.g003