Porphyromonas gingivalis Differentially Modulates Cell Death Profile in Ox-LDL and TNF-α Pre-Treated Endothelial Cells
Fig 7
Differential modulation of the EC death related caspase activity after infection with Pg and its LPS in Ox-LDL and TNF-α pre-treated cells.
(A) Enzymatic activity of Caspase-1, -3 and -9 in HUVECs infected with Pg at a MOI of 100 or with heat inactivated Pg and stimulated by Pg-LPS (1μg/ml) or E.Coli-LPS (1μg/ml) at 24h. (B) Enzymatic activity of Caspase-1, -3 and -9 in Ox-LDL pre-treated HUVECs at 24h. (C) Enzymatic activity of Caspase-1, -3 and -9 in in TNF- α pre-treated HUVECs at 24h. Data were expressed as mean ± SD. *: difference between non-stimulated/infected and stimulated/infected cells, p < 0.05.