Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types
Fig 4
Statistical anaylsis of each 4 base in human T cell-released exosome-dominant miRNA sequences.
(A) The percentage of each base in exosomal miRNAs and donor T cell miRNAs is indicated by different colors, and lined up in order from the highest value of exosomal miRNAs or donor T cell miRNAs, or the highest exosomal/donor T cell miRNA ratio. (B) Pearson’s correlation test was performed to confirm statistical significance of the G-rich feature of human T cell-released exosome-dominant miRNA sequences. The correlation coefficient (r) and p-value were calculated between the percentage of each base (U, C, A or G) and the exosomal miRNA values, donor T cell miRNA values, or exosome/donor T cell miRNA ratios.