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Urinary Exosomal microRNA-451-5p Is a Potential Early Biomarker of Diabetic Nephropathy in Rats

Fig 7

Kidney tissue levels of IL-6 and MMP-9 in rats.

Bar graphs showing average fold expression of (A) IL-6 and (B) MMP-9 in kidney-tissue from untreated diabetic (DM), non-diabetic control (CTRL) and insulin treated diabetic rats (DM + INS) at 10th week of the study 1 (n = 6-10/group). *p≤0.05 versus DM+ INS and δ p≤0.05 versus CTRL by One-Way ANOVA followed by pair wise multiple comparison testing (n = 6-10/time point).

Fig 7

doi: https://doi.org/10.1371/journal.pone.0154055.g007