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Metabolomics Revealed an Association of Metabolite Changes and Defective Growth in Methylobacterium extorquens AM1 Overexpressing ecm during Growth on Methanol

Fig 2

Comparison of the intermediates involved in the serine cycle, the TCA cycle and the ethylmalonyl-CoA pathway between the NG107 strain (Red) and NG115 strain (Green) grown on methanol.

(A) Intracellular metabolites. (B) Supernatant metabolites. The y axis of (A) and (B) is the ratio of the abundance of the NG115 strain to the NG107 strain. The average value for the NG107 strain was set to 1. Data show the mean with error bars indicating standard deviation calculated from three independent biological replicates.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0154043.g002