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Evaluation of Liver Ischemia-Reperfusion Injury in Rabbits Using a Nanoscale Ultrasound Contrast Agent Targeting ICAM-1

Fig 10

Immunohistochemistry shows that no obvious ICAM-1 staining (200×, 400×) is seen in the liver samples of the SO group (A, B); and ICAM-1 has a high expression in periportal endothelial cells (arrow), liver sinusoidal endothelial cells (arrow), and some hepatocytes (arrow) in the I/R group, with significantly deep staining and expanded area (200×, 400×) (C, D).

Fig 10

doi: https://doi.org/10.1371/journal.pone.0153805.g010