Viral Evolved Inhibition Mechanism of the RNA Dependent Protein Kinase PKR's Kinase Domain, a Structural Perspective
Fig 7
Electrostatic potential maps of the binding surfaces of PKR complexes.
The electrostatic potential maps of the binding surfaces along with the activation loop of PKR are shown for the selected stuctres from the free energy landscape plot. Figs 1, 3 and 5 indicate PKRpp bound to eIF2α, K3L and TAT. Figs 2, 4 and 6 indicate PKRp bound to eIF2α, K3L and TAT. The region in red color indicate high electronegative regions and the regions in blue color indicate electropositive regions. The color bars are calibrated in kcal/mol/e.