Genomic Characterization and Comparison of Multi-Regional and Pooled Tumor Biopsy Specimens
Fig 1
Schematic overview of the comparison of mutation and expression patterns from multiregion sequencing of whole-exome and whole-transcriptome.
Regional samples of each cancer were closely grouped over 2-D space based on principal component analysis (PCA). The differences in genomic variants and in gene expression between sequencing are shown.