Constructing Hypothetical Risk Data from the Area under the ROC Curve: Modelling Distributions of Polygenic Risk
Fig 4
Receiver operating characteristic (ROC) curves from empirical prediction studies and from simulated data based on their AUC values.
The ROC curves in black were obtained from the cited articles, the red ones are based on simulated data for the same value of the area under the ROC curve (AUC; A. 0.69 [20]; B. 0.70 [21]; C. 0.57 [22]; D. 0.86 [23]). The lines were pasted in the (empty) plots anchoring the beginning and end of the line at (0,0) and (1,1).