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Clusterin/Akt Up-Regulation Is Critical for GATA-4 Mediated Cytoprotection of Mesenchymal Stem Cells against Ischemia Injury

Fig 3

MSC^GATA-4 transfected with Clu-siRNA (MSC^siRNA-Clu) and transfected with negative control siRNA (MSC^siRNA-NC) were exposed to hypoxia for 72 h.

A. The expression of clusterin in MSC^siRNA-Clu and MSC^siRNA-NC; B. LDH release; C. MTs intake; D. Ratio of LDH to MTs. *, p < 0.05 vs MSC^siRNA-NC. MSC^si-Clu = MSC^siRNA-Clu; MSC^si-NC = MSC^siRNA-NC.

doi: https://doi.org/10.1371/journal.pone.0151542.g003