Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence
Fig 5
Effect of PTEX88 knockdown on protein export in P. berghei.
A: Immunofluorescence assays showing the P. berghei proteins PBANKA_114540 and PBANKA_122900 are still exported after conditional depletion of PTEX88 in PbPTEX88iKD parasites using ATc. Export was measured by calculating MFI, shown as the mean + SEM. B: Surface labelling of parasite antigens on PbPTEX88 iKD parasites harvested between 4 or 5 days post infection compared with infected erythrocytes not exposed to ATc as measured by FACS (n = 6). A mixed ANOVA was used to test for statistical significance.