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Lentivirus-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth and Induces Apoptosis through MAPK Pathways in Human Retinoblastoma Cells

Fig 2

AEG-1 expression in retinoblastoma (RB); 2A: Equivalent amounts of RNA were analyzed by RT-PCR in three RB cell lines (WERI-RB1, SO-RB50, Y79) and in retinal pigment epithelium cells (RPE) as controls. Results were presented as mean ± standard error, obtained in three independent experiments; * indicated the statistical difference between the retinal pigment epithelium cells (RPE) and each of the RB cell lines and between the RB cell lines (P<0.05). 2B: AEG-1 and GAPDH protein levels in untreated cell lines.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0148763.g002