Low Cardiac Output Leads Hepatic Fibrosis in Right Heart Failure Model Rats
Fig 5
Pathological investigation and hepatic fibrosis ratio.
(A) The liver of sham-operated controls stained using Masson-Trichrome stain (original magnification ×4). (B) The liver of PAB stained using Masson-Trichrome stain (original magnification ×4). (C) The liver of sham-operated controls stained using Masson-Trichrome stain (original magnification ×10). (D) The liver of PAB stained using Masson-Trichrome stain (original magnification ×10). (E) PAB rats (n = 12) compared with sham-operated controls (n = 10) for hepatic fibrosis ratio (mean ± SEM). (F) Divided the PAB group into two groups: PAB with preserved CO group (CO≥60 ml/min, n = 6) and PAB with reduced CO group (CO<60 ml/min, n = 6). Hepatic fibrosis ratio was significantly increased in PAB with reduced CO group (mean ± SEM). PAB: pulmonary artery banding.