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An Appraisal of Proliferation and Apoptotic Markers in Papillary Thyroid Carcinoma: An Automated Analysis

Fig 4

Proportion of tumor cells immunolabeled for cyclin D1.

The percentage of tumor cells showing cyclin D1 immunolabeling is indicated in normal thyroid tissue and each case of the various types of papillary thyroid carcinomas: encapsulated and unencapsulated follicular variant of papillary thyroid carcinoma (FVPTC), well differentiated tumor of unknown malignant potential (WDT-UMP), papillary microcarcinoma (PMC) and metastatic papillary thyroid carcinoma (metastatic PTC). Bars indicate the medians. *, p<0.05. The large asterisk above normal thyroid tissue indicates significant difference between the normal tissue and any other variant of PTC.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0148656.g004