In Silico Analysis of the Structural and Biochemical Features of the NMD Factor UPF1 in Ustilago maydis
Fig 1
UPF1 organization is very similar in Ustilago maydis and Homo sapiens.
A) Schematic representation of the domain arrangement for UPF1 in Ustilago maydis (umUPF1) and Homo sapiens (hUPF1). The CH domain (green) is responsible for the interaction with UPF2, eRF1 and eRF3. The helicase region contains two RecA domains (yellow). Additional regulatory domains include domain 1B (orange) and domain 1C (red). The amino acid position is shown for the beginning and the end of each peptide. B) The relative position for each domain in both H. sapiens and U. maydis is presented with a summary of the main features reported for the human factor. Positions for the human factor correspond to isoform 1 (Q92900-1).