A Nonsynonymous/Synonymous Substitution Analysis of the B56 Gene Family Aids in Understanding B56 Isoform Diversity
Fig 3
A Sliding Window Analysis for the Broader B56 Family, or the B56-1 and B56-2 Subfamilies, Revealed Selective Pressures at a Finer Level.
A fifty amino acid sliding window was employed to determine dN (red), dS (green), and dN/dS (blue) values for the entire gene family (all: B56α, B56β, B56γ, B56δ, and B56ε), or the B56 subfamilies (B56-1 and B56-2). Dashed lines demarcate the core domain. The data were superimposed on a pictorial representation of the structure of the B56 conserved core domain with each number above a lightly hued bar denoting a pseudo-HEAT repeat and the darker bars within those representing α-helices.