A Risk Assessment of the Jaffe vs Enzymatic Method for Creatinine Measurement in an Outpatient Population
Fig 1
Overview of experimental design.
We randomly selected 529 patient samples from outpatient samples that were submitted to the laboratory for SCr measurements (Population 1). This group of samples was used for the method comparison study and to evaluate the analytical precision of the Jaffe and enzymatic methods. We estimated biological variability in the outpatient population by identifying all outpatients who had at least two SCr measurements in 2013 (Population 2). This group contained 13,243 patients with a total of 42,195 SCr measurements. We evaluated the magnitude of discordances (standardized discordances) and the frequency of discordances (expected discordance vs observed discordance).