Alpha Adrenergic Induction of Transport of Lysosomal Enzyme across the Blood-Brain Barrier
Fig 5
Combined effect of alpha1 (cirazoline) and alpha2 (clonidine) adrenergic receptor agonists on I-PGUS transport across the BBB.
Neither drug alone affected I-PGUS uptake, but combined they effectively increased transport across the BBB. ***p<0.001 in comparison to control; n = 12/group.