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Alpha Adrenergic Induction of Transport of Lysosomal Enzyme across the Blood-Brain Barrier

Fig 4

Effects of adrenergic antagonists on epinephrine-induced BBB disruption.

Blockade of alpha2 (yohimbine) and beta (propranolol) but not of alpha1 (benoxathian) receptors prevented epinephrine-induced BBB disruption. *p<0.05 in comparison to Control; **p<0.01 in comparison to control; #p<0.05 in comparison to epinepthrine; n = 8/group.

Fig 4

doi: https://doi.org/10.1371/journal.pone.0142347.g004