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Genotoxicity and Cytotoxicity Evaluation of the Neolignan Analogue 2-(4-Nitrophenoxy)-1Phenylethanone and its Protective Effect Against DNA Damage

Fig 1

Assessment of the genotoxic activity of the neolignan analogue 2-(4-nitrophenoxy)-1phenylethanone (4NF) in mouse peripheral blood leukocytes using the comet assay estimated by the parameters percentage of DNA in the tail, tail moment, and Olive tail moment.

SAL, saline (negative control); DMSO, dimethylsulfoxide (negative control); CP, cyclophosphamide (50 mg/kg) (positive control). * p < 0.05, ** p < 0.01 compared to the negative control.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0142284.g001