Ocular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model Systems
Fig 2
Histologic analysis of human anterior segment ocular tissue following treatment with cromakalim.
A, B) 1 μm toluidine blue stained representative sections of vehicle (DMSO) and cromakalim treated eyes. C, D) Transmission electron micrographs showing ultrastructure of vehicle and cromakalim treated eyes. Vehicle and treated eyes had similar morphology and ultrastructural appearance showing no detrimental side effects of cromakalim treatment. SC = Schlemm’s canal; TM = trabecular meshwork; AC = anterior chamber; JCT = juxtacanalicular region.