Therapeutic Effects of α1-Antitrypsin on Psedumonas aeruginosa Infection in ENaC Transgenic Mice
Fig 2
Effects of alpha1 antitrypsin (A1AT) on lung inflammation and Pseudomonas aeruginosa (PA) load in wild-type mice after 1 day of infection.
Mice were infected with PA as described in Materials and Methods, and treated at 2 h post PA infection with A1AT. After 1 day of PA infection, mice (n = 6 mice/group) were sacrificed to determine inflammation (A, B, C, D) and PA load (E, F) in bronchoalveolar lavage (BAL) fluid and lung tissue. BSA = bovine serum albumin, serving as a protein control for A1AT. Data are presented as means ± SEM.