CD8+ T Cells Mediate Female-Dominant IL-4 Production and Airway Inflammation in Allergic Asthma
Fig 2
Sex differences in cytokine production in lung.
Male and female WT mice (A) and CD8KO mice (B) were sensitized and challenged. IL-2, IL-4, IL-5, IL-13 and IFN-γ levels in the lung were measured by ELISA one day after OVA challenge. Data are shown as the mean ± SEM from at least three independent experiments (n = 8–11). Open bars, male mice; closed bars, female mice. *, P < 0.05; **, P < 0.01; NS, not significant.