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Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression

Fig 5

Modulation of MGMT expression by O6-BG in SF268 and SK-N-SH tumor cell lines.

A) Western blot analysis of the MGMT expression after treatment with TMZ, O6-BG and both TMZ + O6-BG. B) Relative growth rates of SF268 and SK-N-SH cell lines with and without O6-BG treatment after TMZ treatment. B: basal cells, O6BG: cell line treated with O6-BG. All data represent the mean value ± SD of triplicate cultures.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0140131.g005