Downhill Running-Based Overtraining Protocol Improves Hepatic Insulin Signaling Pathway without Concomitant Decrease of Inflammatory Proteins
Fig 5
Protein levels (arbitrary units) of IL–6 (A), IL–10 (B), IL–15 (C), TNF-alpha (D), SOCS3 (E) and their respective β-actin controls for the experimental groups. Ratio between pIKKalpha/beta (Ser180/181)/IKKbeta (arbitrary units) (F), and ratio between pSAPK-JNK (Thr183/Tyr185)/SAPK-JNK (arbitrary units) (G) for the experimental groups. Data correspond to means ± SE of n = 6 mice. CT: sedentary mice; OTR/down: overtrained by downhill running; OTR/up: overtrained by uphill running; OTR: overtrained by running without inclination.*P < 0.05 vs. CT.