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Intermittent Administration of Parathyroid Hormone [1–34] Prevents Particle-Induced Periprosthetic Osteolysis in a Rat Model

Fig 8

TRAP staining images from the three groups.

(A) Blank group, well-formed bone–implant integration with trabecular bone surrounding the implant; (B) control group, obvious osteolysis and local trabecular bone disruption (red arrows) were observed at the bone–implant interface; and (C) improved bone–implant integration with thicker trabecular bone and reduced trabecular bone disruption (red arrows) were observed.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0139793.g008