< Back to Article

Lack of Cytosolic Carboxypeptidase 1 Leads to Subfertility due to the Reduced Number of Antral Follicles in pcd^3J-/- Females

Fig 1

Adult onset ovarian hypoplasia in pcd^3J-/- mice.

(A) Comparison of pcd^3J+/+ and pcd^3J-/- females revealed a decrease in ovary size at 8 weeks of age. (B) Comparison of relative ovary to body weight differences of pcd^3J-/- females at P18, 4 weeks old, and 8 weeks old, compared to pcd^3J+/? mice. The ratio of ovary weight to body weight is presented as the mean ± S.E. Numbers in parentheses indicate the number of mice examined. The difference was statistically significant at 8 weeks of age (P < 0.001).

doi: https://doi.org/10.1371/journal.pone.0139557.g001