ERBB3 Positively Correlates with Intestinal Stem Cell Markers but Marks a Distinct Non Proliferative Cell Population in Colorectal Cancer
Fig 6
ERBB3+ colorectal cancer cells are predominantly non proliferative in contrast to EPHB2+ cells.
(A and B): Detection of EPHB2 (green), ERBB3 (red) and KI-67 (grey) by co-immunofluorescence in two representative colorectal cancer samples (DAPI, blue). (C): Distribution of P-H3+ proliferative cells within the 4 distinct cell populations in 8 colorectal cancer samples. (D and E) Detection of EPHB2 (green), ERBB3 (red) and P-H3 (grey) by co-immunofluorescence in two representative colorectal cancer samples (DAPI, blue). Scale bar, 50μm.