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A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Fig 2

Changes in 6-TGN concentrations in RBCs (pmol/8×108 RBCs) over time for the various groups.

a The average concentration of 6-TGN in the group with 94C>A tended to be higher than that in the group without 94C>A. However, there was no statistically significant difference between the groups. b c d There were no statistically significant differences between the groups with and without adverse reactions (ARs) or the groups with and without leukopenia or between the males and females.

Fig 2

doi: https://doi.org/10.1371/journal.pone.0137798.g002