Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy
Fig 1
Network models of lipoproteins and clinical variables in control subjects and in T1D subjects.
Control (1A) and T1D subjects (1B). Integration of datasets was accomplished with the Cytoscape tool (www.cytoscape.org), which constructs and displays correlation networks between components (p-value < 0.005 and thresholds R > ± 0.5 for clinical variables, and R > ± 0.7 for lipoprotein variables). Continuous lines represent positive correlations, and dashed lines represent negative associations. Grey spheres represent clinical variables; in red, LDL related lipoproteins; in green, HDL lipoproteins; in blue, VLDL lipoproteins; and in purple, total triglycerides. Orange circles mark the variables that are reduced in T1D subjects.