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The UVB-Stimulated Expression of Transglutaminase 1 Is Mediated Predominantly via the NFκB Signaling Pathway: New Evidence of Its Significant Attenuation through the Specific Interruption of the p38/MSK1/NFκBp65 Ser276 Axis

Fig 1

Effects of UVB radiation on the gene and protein expression levels of TGase 1.

HPKs were exposed to UVB at a dose of 80 mJ/cm2 and were cultured for 24 and 48 h and then analyzed by real-time RT-PCR and Western blotting, respectively. (A) The gene expression level. RT-PCR results are normalized to GAPDH; values are means ± S.D. derived from 3 independent experiments. **: p<0.01. (B) The protein expression level. Representative immunoblots from 3 independent experiments are shown; values are means ± S.D. derived from 3 independent experiments. **: p<0.01.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0136311.g001