Carnosol Inhibits Pro-Inflammatory and Catabolic Mediators of Cartilage Breakdown in Human Osteoarthritic Chondrocytes and Mediates Cross-Talk between Subchondral Bone Osteoblasts and Chondrocytes
Fig 1
Effect of Carnosol on Chondrocyte Gene Expression.
(A) COL2A1, (B) ADAMTS-4, (C) ADAMTS-5. Gene expression was normalized to GAPDH. The results are expressed as the mean ± SD of three experiments performed with cells coming from three different donors. ANOVA with Tukey posttest performed between treated and untreated cells, * = p<0.05, ** = p<0.01 and *** = p<0.001.