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Hypertonic Saline Dextran Ameliorates Organ Damage in Beagle Hemorrhagic Shock

Fig 5

Systemic oxygenation parameters in the LR, HSD and HSD+LR groups presented at baseline (BL, time = -90 min), end of controlled bleeding (post-hemorrhage, PH, time = 0 min), end of pre-hospital resuscitation (Resuscitation1, R1, time = 60 min), end of in-hospital resuscitation (Resuscitation2, R2, time = 120 min), and 3 h after in-hospital resuscitation (Resuscitation3, R3, time = 240 min).

(A) Systemic oxygen transport (DO2). (B) Systemic oxygen uptake (VO2). (C) Central venous oxygen saturation (ScvO2). (D) Venous-to-arterial CO2 gradient (Pv-aCO2). (E) Arterial lactate (Lac). (F) Hb concentration. *P<0.05 vs LR; #P<0.05 vs HSD. n = 7 for all groups.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0136012.g005