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Elevated Levels of Asymmetric Dimethylarginine (ADMA) in the Pericardial Fluid of Cardiac Patients Correlate with Cardiac Hypertrophy

Fig 1

L-Arg and asymmetric dimethylarginine (ADMA) in plasma of non-cardiac patients (NCP) (n = 20), and in plasma and pericardial fluid (PF) of patients undergoing coronary artery bypass graft (CABG, n = 28) or valve replacement (VR, n = 25) surgery.

(A) Levels of L-Arg in plasma and PF. (B) Levels of ADMA in plasma and PF. (C) ratios of L-Arg and ADMA in plasma and PF. Mean ±SEM. * indicates significant (p<0.05) differences between CABG and VR patients. Substrate availability indicated by the ratio, which is significantly increased in CABG compared to NCP and VR.

Fig 1

doi: https://doi.org/10.1371/journal.pone.0135498.g001