Quantitative Analysis of Differential Proteome Expression in Bladder Cancer vs. Normal Bladder Cells Using SILAC Method
Fig 3
Distributions of proteins identified in various experiments described in the text.
(A) Venn diagrams of numbers of identified proteins from individual experiments. (B) Ratios of KK47/HCV29 (M/L) and YTS1/HCV29 (H/L) for the set of 1766 proteins. log2 of the SILAC ratio for each protein (n = 2) reflects differences in relative expression among KK47, YTS1, and HCV29 cells. (C) Distribution of SILAC M/L ratios. (D) Distribution of SILAC H/L ratios. (E) Cluster graph ("heat map") generated by hierarchical clustering of significant regulated proteins after averaging z-scores using a 95% cutoff.