Lineage-Specific Changes in Biomarkers in Great Apes and Humans
Fig 3
Liver UGT1A1-mRNA expression in mice on raw and cooked diets:
Liver mRNA expression of UGT1A1 transcripts in mice fed either a raw or cooked meat or raw or cooked or tuber diets was measured by RNA-Seq [49]. Total RNA was prepared from 17 individuals and sequenced as a pool on two lanes of an Illumina HiSeq 2500. Significant differences in expression between mice fed raw diets and mice fed cooked diets were quantified using DESeq [48].