Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma
Fig 1
(A) Patients grouped according to the ABCB1 3435C/T, 1236C/T, 2677G/T haplotype; median PFS was 2.4 months for homozygous carriers of the TTT haplotype and 8.4 months for other cases (P = 0.001). (B) Patients grouped according to the ABCB1 3435C/T, 1236C/T, 2677G/TA haplotype; median OS was 4.6 months for homozygous carriers of the TTT haplotype and 19.6 months for other cases (P = 0.005).