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Combined Scintigraphy and Tumor Marker Analysis Predicts Unfavorable Histopathology of Neuroblastic Tumors with High Accuracy

Table 4

Performance of TLCRR, NSE and combined analysis for prediction of unfavorable histopathology.

Sensitivity (SE), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), and accuracy (AC) are each given in percent using optimal cut-off as determined by ROC analysis. Relative risk (RR) was calculated. TLCRR = tumor-to-liver count-rate ratio, NSE = neuron-specific enolase, ROC = receiver-operating-characteristic.

Table 4

doi: https://doi.org/10.1371/journal.pone.0132809.t004