Age-Related Gene Expression Differences in Monocytes from Human Neonates, Young Adults, and Older Adults
Fig 7
Elevated expression of a broad range of inflammatory genes prior to stimulation of freshly isolated monocytes from older adults.
(A) LPS-induced genes exhibiting differential basal expression between adults and older adults (n = 189) are grouped according to maximum mRNA level. Columns 7 and 8 show the ratio of transcript levels between older adults and young adults before stimulation and at maximum transcript levels, respectively. (B) The average relative transcript levels within each cluster and for each age are shown.