Antioxidant Properties of Whole Body Periodic Acceleration (pGz)
Fig 3
The Expression and Translocation of Nrf2 Transcription Factor after pGz Treatment.
This figure depicts the expression and translocation of Nrf2 transcription factor after 4 wk of daily pGz or no pGz (CONT) (A). pGz significantly increased upregulation of the Antioxidant Response Element transcription factor Nrf2 compared to CONT (*p< 0.01) (B). Translocation of Nrf2 is expressed as the ratio of Nrf2 in nucleus and cytosol. pGz also significantly increased Nrf2 translocation to nucleus compared to CONT (*p< 0.01). Representative Immunoblots of Nrf2 in nucleus and cytosol with respective protein loading controls Anti-Laminin B1 (nucleus) and Anti-α Tubulin (cytosol) in CONT and pGz groups showed increased protein expression of Nrf2 in nucleus of pGz treated mice. Optical Units = O.U.