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BMI1 Is Expressed in Canine Osteosarcoma and Contributes to Cell Growth and Chemotherapy Resistance

Fig 8

Effect of PTC-209 treatment on viability of canine OSA cell lines.

MTT assay showing dose dependent decreases in cell viability following 72hrs of PTC-209 treatment. Absorbance data is shown as a percent of untreated (UT) control cells. Error bars reflect SD and statistical analysis was performed using 2-way ANOVA with Tukey’s multiple comparisons test. p-values reflect significance as compared to vehicle control.** p<0.01, **** p<0.0001.

Fig 8

doi: https://doi.org/10.1371/journal.pone.0131006.g008