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Mest but Not MiR-335 Affects Skeletal Muscle Growth and Regeneration

Fig 6

Muscle satellite cells are not affected in Mest+/- mice.

(A) Numbers of Pax7 positive-satellite cells per muscle fiber in sections of TA muscles of WT, Mest+/-, and miR-335+/Neo mice (n = 3 per genotype) at 10 weeks old in normal condition and 14 day after CTX. (B) qRT-PCRs for Pax7 and MyoD mRNA were performed in normal TA muscles of 11–13 weeks old WT, Mest+/-, and miR-335+/Neo mice (n = 3 per genotype). Error bars indicate the s.e.m. *P < 0.05 compared with WT mice.

Fig 6

doi: https://doi.org/10.1371/journal.pone.0130436.g006