Cortical and Subcortical Grey and White Matter Atrophy in Myotonic Dystrophies Type 1 and 2 Is Associated with Cognitive Impairment, Depression and Daytime Sleepiness
Fig 4
ESS and brain grey and white matter in DM2.
a) Significant negative correlations between GM and WM and Epworth sleepiness score in 15 DM2 patients detected by voxelwise multiple regression analysis. Age was used as a covariate of no interest. Clusters with FWE corrected cluster p-values < 0.07 are depicted; MNI coordinates: negative X-values reflect left side and positive X-values right sided location. b) Scatterplot of global brain GM and WM in dependency on ESS; the lines and annotations reflect the results of the linear regression analysis.