Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge
Fig 6
H7N7 influenza viral titers in lungs at 5 day post challenge following subcutaneous immunization.
Viral titer measurement in lungs of at 5 day post challenge following mice challenged with 5MLD50 of H7N7 influenza virus after subcutaneous immunization. The results of viral titers in lungs were expressed in terms of mean value of log10TCID50/g (n = 3) ± standard deviation (SD). (a-when compared with wild-type H7N7 Bac-HA vaccine group, ** P<0.001).