MicroRNA-206: Effective Inhibition of Gastric Cancer Progression through the c-Met Pathway
Fig 2
Ectopic miR-206 induces G1 arrest and inhibits cell proliferation, migration and invasion.
(A) MTS cell proliferation assay was carried out on day 3 as indicated. (B) AGS cells were assessed with Transwell and Matrigel assays. The number of cells that had migrated through the culture insert pores (left) or had invaded through the Matrigel insert pores (right) was quantified by counting five independent visual fields. *: Differences in cell migration or invasion between miR-206 and negative control transfected cells were significant, P < 0.01.