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Proteomic Investigation of the Response of Enterococcus faecalis V583 when Cultivated in Urine

Fig 5

Gene context analysis.

The figure shows the gene context around ef0764 (indicated in red) as well as (potentially) related gene clusters in other gram-positive bacteria. Two genes upstream of ef0764, uvrA and uvrB (green), are involved in DNA repair and the downstream gene cluster of unknown function (orange box) commonly co-occurs with these known DNA repair genes. This cluster potentially encodes a predicted P-loop-containing kinase, a CofD-like protein and a cytoplasmic hypothetical protein. Genes in grey are genes that do not show similarity to other genes in this specific region of the genomes shown; while some have annotated functions, their genomic location is not conserved, nor associated with the location of uvrA and uvrB. The ef0764 gene shows no similarity to the gene located in a similar position in L. brevis, and BLAST analysis could not identify any homologues in any other species.

Fig 5

doi: https://doi.org/10.1371/journal.pone.0126694.g005