Discovery of an Inhibitor of Z-Alpha1 Antitrypsin Polymerization
Fig 1
Kinetic diagram of bPEG-peptide binding to α1AT.
(A) Four micrograms per well of attached (■) Z-α1AT or (●) M-α1AT were incubated for various times in presence of 38.4 μM bPEG-peptide. (B) Z-α1AT was incubated in presence of 5% DMSO and bPEG-peptide for 16 h. Errors bars reflect the standard deviation of three replicates.