Perilipin1 Deficiency in Whole Body or Bone Marrow-Derived Cells Attenuates Lesions in Atherosclerosis-Prone Mice
Fig 2
Lipid content is decreased in peritoneal macrophages and foam cells derived from Plin1-/- mice.
Peritoneal macrophages from Plin1+/+ and Plin1-/- mice were incubated for 48 hours in the absence or presence of 50 μg/ml aggLDL. (A and B) The contents of free cholesterol (FC), cholesterol ester (CE) and triglyceride (TG) were measured. n = 4,*P < 0.05. (C) Nile red staining of LDs in peritoneal macrophages from Plin1+/+ and Plin1-/- mice with aggLDL (50μg/ml) (n = 6).