Capsaicin Enhances the Drug Sensitivity of Cholangiocarcinoma through the Inhibition of Chemotherapeutic-Induced Autophagy
Fig 3
The cytotoxic effect of 5-FU in combination with capsaicin in vivo.
(A) Combination treatment of 5-FU and capsaicin significantly reduced the xenografted CCA tumor volume. (B) Combination treatment with 5-FU and capsaicin effectively suppressed CCA tumor growth. (C) Capsaicin increased 5-FU-induced apoptosis in vivo. Apoptosis was detected by TUNEL assay. * P<0.05, ** P<0.01.