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α1B-Adrenergic Receptors Differentially Associate with Rab Proteins during Homologous and Heterologous Desensitization

Fig 14

Models for α1B-adrenergic-Rab protein interaction.

α1B-Adrenergic internalization and recycling back to the plasma membrane during homologous (panel A) and heterologous (panel B) desensitization is depicted. NA, noradrenaline; α1B-AR, α1B-adrenergic receptor; S1P, sphingosine 1-phosphate; S1P1, sphingosine 1-phosphate receptor type 1. Rab proteins are shown as membrane anchored proteins.

Fig 14

doi: https://doi.org/10.1371/journal.pone.0121165.g014